EP 51. Depression: The Role of Inflammation and Metabolism.

Interview with Dr. José Abellán , interventional cardiologist at the Santa Lucía University General Hospital, science communicator, and one of the clearest and most empathetic voices for understanding cardiovascular health from a preventative perspective . An essential conversation for those who want to learn how to care for their heart with science and practical tools, without extremism or controversy. We discussed topics that are essential for the general population: How a heart attack manifests in men versus women, why the symptoms may be different, what signs we should not overlook, and in order to avoid delays in going to the emergency room. Three key tips to prevent a heart attack. And, for those who have already suffered one, what habits really help recovery and reduce the risk of relapse. Lipoprotein (a): the great unknown marker: what it is, why it doesn't resemble traditional cholesterol, and why 1 in 5 people have elevated levels without knowing it. Its role in residual cardiovascular risk. Tobacco, alcohol and vaping : the real impact on the heart, what current evidence says about each and why the risks of vaping continue to be underestimated. Strength training and hypertension : myth or reality? Dr. Abellán explains whether strength training is safe for people with high blood pressure and what the studies show. To learn, with scientific evidence, how to improve and protect your cardiovascular health starting today. Dr. Abellán's IG: @doctorabellan TikTok Dr. Isabel Viña: @isabelvinabas YouTube Channel Dr. Isabel Viña: YouTube Channel

High Ferritin: Understanding the Link to Fatty Liver and Insulin Resistance Hello, I am Dr. Isabel Viña Bas, a physician and Scientific Director of IVB Wellness Lab. In my clinical practice, high ferritin is one of the findings that causes the most uncertainty. My mission is to help you "know more to fear less and choose better," and that starts with understanding that ferritin, in addition to storing iron, is a messenger of your metabolic state. Frequently, elevated ferritin levels are an acute-phase reactant: a distress signal emitted by the body in the face of chronic inflammation and oxidative stress, rather than a reflection of the iron you consume in your diet. This protein is a direct window into the health of your liver and the efficiency of your metabolism. What does it really mean to have High Ferritin? Medically, ferritin is an intracellular protein that stores iron safely. However, when there is cellular damage or a systemic inflammatory response, ferritin "leaks" into the bloodstream and raises its levels in blood tests. Having high ferritin is a "red flag" that forces us to look beyond the blood. It indicates that there is a process of metabolic pressure, focused primarily on the liver and glucose management. It is a symptom that the redox balance (the scale between oxidation and anti-oxidation) has tipped dangerously toward cellular damage. The Metabolic Triad: Ferritin, Fatty Liver, and Insulin Resistance To address the root of the problem, we must understand how these three pillars interact beneath the surface. The liver under pressure and cellular inflammation The current lifestyle, marked by stress and caloric overload, generates an accumulation of fat in the liver. This hepatic tissue, when saturated, activates chronic inflammatory responses mediated by the NF-κB pathway, a molecular switch that triggers the production of inflammatory cytokines. This state of "liver under pressure" damages hepatocytes, alters the extracellular matrix, and releases ferritin in response to tissue damage. Insulin Resistance: The "distracted" liver Insulin resistance makes this inflammation chronic. A critical factor here is the consumption of alcohol and sugars. Alcohol is a potent hypoglycemic agent, but the most dangerous thing is that it "distracts" the liver. While the liver is focused exclusively on detoxifying us from alcohol, it becomes unable to respond to hormones like glucagon, and this prevents the proper release of glucose into the blood. This constant metabolic stress exhausts cellular reserves and perpetuates the inflammation signal that raises ferritin. Direct relationship The increase in ferritin is, ultimately, the body's response mechanism to lipotoxicity (excess fat) and glucotoxicity. It is the smoke that warns us of an ongoing metabolic fire. Lifestyle Strategies to Reduce Hepatic Inflammation Recovering liver health is a matter of applying science to daily habits: Run from "miracle diets": be wary of claims of losing 3 kg in 24 hours. Glycogen (the way we store carbohydrates in muscle and liver) retains 3 times its weight in water, while salt retains 4 times its weight in water. Diets that drastically eliminate these elements only cause the loss of "intracellular water," not fat, and this stresses the liver even more. Hydroelectrolytic Balance: prioritize foods rich in potassium (avocado, spinach, tomatoes) to naturally balance fluid levels and reduce inflammation. Whole Carbohydrates: are necessary as a source of fiber to improve insulin sensitivity and modulate the inflammatory profile. Physical Activity and Markers: exercise is vital, but it must be modulated. An excess of load without recovery can falsely elevate markers such as CK (creatine kinase), LDH, and, especially, AST (the most abundant transaminase in muscle), which can be confused with liver damage in blood tests. Advanced Approach: Science-Based Supplementation When we seek real recovery, we need active ingredients with high bioavailability that reach where others cannot. Metabolic-Max and Insulin Sensitivity The key to this supplement is the phytosomal Berberine Berbevis®. Unlike traditional berberine, which often "breaks" and becomes inactive in the intestine or liver and causes gastric discomfort, the phytosome system guarantees 10 times higher bioavailability. Effect: improves fat utilization and blood sugar control. It optimizes mitochondrial efficiency and attacks insulin resistance at the root. Anti-OX Global and Hepatic Cellular Protection Anti-OX Global works as a comprehensive strategy against inflammaging: it acts on several fronts at once. Tomato Lycopene: unlike fungal versions, our tomato-derived lycopene contains 11 conjugated double bonds, one of the most potent protectors against fatty liver and LDL oxidation. Astaxanthin (Astabead®): extracted with supercritical CO₂ from microalgae (H. pluvialis) grown in pure Icelandic waters (with very low heavy metal profiles). It integrates into the cell membrane, protects the lipid bilayer, and modulates the NF-κB pathway. NordicCherry®: this tart cherry extract is fundamental for reducing damage markers such as AST, CK, and LDH, so the body recovers without suppressing the positive adaptations of exercise. Coenzyme Q10 (100 mg): optimizes hepatic mitochondrial energy and regenerates vitamins C and E. Recommended Synergy: combining both products makes sense: while Metabolic-Max optimizes glucose metabolism, Anti-OX Global protects the cellular environment and the liver's extracellular matrix and reduces the inflammatory signal that keeps ferritin elevated. Dosage and Safety Guidelines For solid metabolic results, continuous use of at least 3 months is recommended. Product Recommended Dosage Key Instructions Metabolic-Max 1 capsule before main meals Avoids intestinal inactivation; maximum metabolic efficiency. Anti-OX Global 2 capsules daily Take together with a fat-rich meal. Do not open the capsules (to avoid acidity or gastric inactivation). Important Warnings Contraindications: not suitable during pregnancy. Interactions: do not use if you are under treatment with anticoagulants such as acenocoumarol (Sintrom) or warfarin (Aldocumar). High ferritin is an opportunity to pay attention to your metabolic health; there is no need to be alarmed. Optimizing your liver and your insulin sensitivity requires evidence-based tools and consistency, not luck or quick fixes. Transforming your health is a matter of applying science with consistency, day by day. You have in your hands the knowledge necessary to balance your metabolism and regain your vitality. Author: Dr. Isabel Viña Bas  I hope you like it :)For more information, you know you can find me on my Instagram @isabelvina where I share daily content My TikTok @isabelvinabasOn my YouTube channel YouTube ChannelAnd the supplements formulated by me on my website My website

Hello :) In today's episode, and thanks to your loyalty, we are celebrating episode number 100 after more than two years together!!How time has flown... a thousand thanks to everyone who has been with me for however long you've been sharing moments and letting me show you everything I believe can add value to your lives within the complex world of health and medicine.In this special episode, we once again have the presence of Doctor Juan Viña, Doctor and professor of biochemistry and molecular biology at the University of Valencia, and above all: my father.In today's episode, we answer the questions:What are essential amino acids and why are they called "essential"?What role do ghrelin and leptin play as appetite control hormones?What is choline and why is it a key nutrient during pregnancy and breastfeeding?What is S-AMe and what is its key role in metabolism?How has medicine advanced in the last 50 years and the role of artificial intelligence in current medicine? I hope you enjoy it very much :) Let us know :)For more information, you know you can find me on my Instagram @isabelvina where I share daily content My TikTok @isabelvinabasOn my YouTube channel https://www.youtube.com/channel/UC-dfdxLBcvfztBvRAKZSXGQAnd the supplements formulated by me https://ivbwellness.comFor more information, you know you can find me on my Instagram @isabelvina where I share daily content My TikTok @isabelvinabasOn my YouTube channel YouTube ChannelAnd the supplements formulated by me on my website My website

Helloooooo!Happy day and thank you so much for listening :)In today's episode we're going to talk about-Migraines: why they appear, why there are migraines related to the menstrual cycle, what supplements (besides lifestyle changes) can help, such as magnesium, PEA, CoQ10, and riboflavin.-Fructose and sorbitol intolerance: which cases are reversible and how we can reverse it or at least greatly improve it.-Chronic corticosteroid use: what aspects to consider.For more information, you know you can find me on my Instagram @isabelvina where I share daily contentMy TikTok @isabelvinabasThe supplements formulated by me on my website https://ivbwellness.comOn my YouTube channel https://www.youtube.com/channel/UC-dfdxLBcvfztBvRAKZSXGQFor more information, you know you can find me on my Instagram @isabelvina where I share daily contentMy TikTok @isabelvinabasOn my YouTube channel YouTube ChannelAnd the supplements formulated by me on my website My website

Hola! In today's episode, I'll tell you about the reversible and/or manageable causes of chronic fatigue.If you feel that no matter how much you sleep, you take care of your diet and exercise to the fullest, and you still feel like a truck ran you over, this episode can help you a lot.In the podcast, I talk about which supplements can help you with the different causes or factors. I'm writing them down here so that if my pronunciation isn't the clearest, you have them in writing : )Chronic stress: Reishi, schizandra, eleuthero, rhodiola, ashwagandha, and theanine.Key micronutrients: Magnesium, Vitamin B12 (in methylcobalamin form if possible), iron, vitamin D3K2, vitamin B1 (thiamine), Coenzyme Q10.For more information, you know you can find me on my Instagram @isabelvina where I share daily content.On my YouTube channel https://www.youtube.com/channel/UC-dfdxLBcvfztBvRAKZSXGQ And the supplements formulated by me https://ivbwellness.comFor more information, you know you can find me on my Instagram @isabelvina where I share daily content.My TikTok @isabelvinabasOn my YouTube channel YouTube ChannelAnd the supplements formulated by me on my website My website

Hellooo :) In today's episode I have the pleasure of chatting with Dr. José Luis Ramírez, a specialist in dermatology, with extensive experience in the treatment of acne, rosacea and in the use of laser therapies. Throughout the episode we address the most frequent reasons why people between the ages of 25 and 65 visit the dermatologist today, and how stress, environmental pollution or sun exposure directly influence skin health. We also discussed the most notable differences between female and male skin throughout the different stages of life, and how to adapt skin care to each age. We delve into the world of dermatological lasers: why the same technology can be used for acne, blemishes, wrinkles, or sagging skin; which types of lasers are most effective depending on the indication; what expectations are realistic before starting treatment; and how to minimize risks. We also compare blue light and infrared treatments with lasers and analyze in which cases they can be complementary. Furthermore, and in keeping with José Luis's extensive experience, we dedicate a significant portion of the episode to acne: from its management in adulthood to topical treatments, dietary supplements, laser therapies, and the most effective medications. Dr. Ramírez explains how long it is advisable to maintain treatments like isotretinoin and whether, once completed, the skin changes can be long-lasting. Finally, we share practical advice on three basic pillars for skin care from age 25 onwards, the most common mistakes to avoid, the most useful supplements for skin health, as well as other lifestyle measures with the greatest positive impact on the skin. Here is Jose Luis's contact information if you wish to contact him and schedule an appointment: Dermatologist at IMR, Madrid. Director of the Scar Treatment Unit. Instagram: @dr.ramirezbellver For more information, you know you can find me on Instagram @isabelvina where I share daily content. My TikTok @isabelvinabas On my YouTube channel And the supplements I've formulated are on my website . My website

Hellooooo:), welcome back to another episode of the podcast and the start of a new season, which comes with some very important new features: among them, the addition of video format and the presence of very special guests, both on a personal and professional level. And I think there could be no better person to accompany me at this beginning than Dr. Teresa Bas: spine surgeon, expert in the treatment of scoliosis in adults and children, head of the Spine Unit at the La Fe University Hospital in Valencia, associate professor at the University of Valencia and, also, my mother. In today's episode, we'll learn what lower back pain is, its various causes, what distinguishes it from sciatica, and how these problems are addressed medically and surgically. We'll also explore lifestyle changes and supplements that can help improve lower back pain, herniated discs, and sciatica, as well as the crucial role of exercise and nutrition in spinal health. And last but not least, we'll discuss the differences in spinal pathology between women and men. I hope you find it useful and learn a lot. My mother's Instagram handle is @dra.teresabas His private practice is Clinica Bas, located at Joaquin Costa 42 in Valencia, Spain. His work at the hospital is in the Spine Unit at the La Fe University and Polytechnic Hospital in Valencia, Spain. For more information, you know you can find me on Instagram @isabelvina where I share daily content. My TikTok @isabelvinabas On my YouTube channel And the supplements I've formulated are on my website . My website

Hellooo :)In this latest episode of the season, we discuss one of the most frequent (and misunderstood) topics in medical consultations: the chronic use of proton pump inhibitors (PPIs) like omeprazole, pantoprazole, esomeprazole, as well as H2 blockers like famotidine, often for gastrointestinal issues such as dyspepsia or reflux. But first, I'll explain which cells produce acid, why we need it, and what can happen when we block it for too long. I'll also cover the causes behind symptoms like reflux, dyspepsia, or heavy digestion, and when it makes sense to use PPIs on a short-term or longer-term basis.Additionally, I'll try to review the diagnostic algorithm for different clinical cases (reflux, esophagitis, functional dyspepsia, eosinophilic esophagitis) with you, and we'll discuss situations where dietary supplements or lifestyle adjustments might be helpful.Everything with a clear goal: neither to demonize nor idealize these medications, but to understand well how and when to use them.I hope you enjoy it and, above all, find it very useful :)For more information, you know you can find me on my Instagram @isabelvina where I share daily content My TikTok @isabelvinabasOn my YouTube channel https://www.youtube.com/channel/UC-dfdxLBcvfztBvRAKZSXGQAnd the supplements formulated by me https://ivbwellness.comFor more information, you know you can find me on my Instagram @isabelvina where I share daily content My TikTok @isabelvinabasOn my YouTube channel YouTube ChannelAnd the supplements formulated by me on my website My Website

Hello!!! In today's podcast, I'll try to share tips you can apply to maintain all the health gains you've made with your lifestyle routine throughout the year. This way, if you wish, you can fully enjoy the summer while minimizing the metabolic and overall health losses that can be associated with typical summer routines, where we can't be as diligent with our exercise, diet, and other lifestyle measures. It's not necessary to apply them all, or all at once. The important thing is to be aware of them so that, if we wish, we can apply them. Ideally all of them, but if not, any you can apply, even for just a couple of days, will always be beneficial. Every little helps. Every stone makes a wall. I hope you like it. Big kisses!! For more information, you know you can find me on Instagram @isabelvina where I share daily content. My TikTok @isabelvinabas On my YouTube channel https://www.youtube.com/channel/UC-dfdxLBcvfztBvRAKZSXGQ And the supplements formulated by me https://ivbwellness.com For more information, you know you can find me on Instagram @isabelvina where I share daily content. My TikTok @isabelvinabas On my YouTube channel And the supplements I've formulated are on my website . My website

Hola :)Hoy vamos a hablar de la salud biliar Espero que este episodio del podcast sobre la salud biliar os aporte luz y claridad sobre un tema tan importante… y a menudo tan olvidado.A lo largo del episodio aprenderás dónde se produce la bilis, cuáles son sus funciones, cuál es su composición y por qué es tan importante su almacenamiento en la vesícula biliar.También te contaré qué estímulos provocan su liberación, cómo es el metabolismo intestinal de la bilis una vez secretada, y por qué es clave la microbiota, el consumo de grasas saludables y fibra para mantener el equilibrio del metabolismo biliar… y del metabolismo global.Asimismo, hablaremos de qué fáctores pueden favorecer la aparición de calculos biliares como el exceso de estrogenos o de colesterol hepatico.Y, por supuesto, hablaremos de algunos complementos alimenticios que pueden ayudar a optimizar el flujo de la bilis, como la taurina, la glicina, el extracto de alcachofa, el cardo mariano o el conocido ácido TUDCA.Espero que os guste y sobre todo os ayude a saber mas para temer menos y elegir mejor :)Para mas información ya sabéis que me tenéis en mi instagram @isabelvina dónde te comparto contenido diario Mi TikTok @isabelvinabas En mi canal de YouTube https://www.youtube.com/channel/UC-dfdxLBcvfztBvRAKZSXGQY los suplementos formulados por mi https://ivbwellness.com-Para mas información ya sabéis que me tenéis en mi instagram @isabelvina dónde te comparto contenido diario Mi TikTok @isabelvinabasEn mi canal de YouTube Canal YoutubeY los suplementos formulados por mi en mi web Mi web