Berberine

WHAT IS BERBERINE USED FOR?

• Improves insulin sensitivity

This is possible because it increases the number of insulin receptors in cells and promotes the translocation of GLUT 4 transporters. These 2 key functions of Berberine will allow your cells to be more sensitive to insulin, making it so that not as much of this hormone is needed to carry out its function: allowing glucose to enter your cells (where it should be), and not into the blood, oxidizing and damaging tissues.

• Increases the oxidation of fatty acids and decreases the synthesis of triglycerides

Because it inhibits the enzyme acetylCoA carboxylase at the level of hepatocytes, this allows fatty acids to go into the mitochondria to be beta-oxidized, preventing triglycerides and toxic intermediate metabolites such as ceramides and DAG from being synthesized.

• Decreases cholesterol synthesis

Inhibits PSCK9 by increasing hepatic uptake of LDLc independently of plasma cholesterol levels.

• Anti-inflammatory effect

Reduces the expression of the inflammatory transcription factor NFkB.

OTHER RELATED BENEFITS:

• Weight Loss: Berberine may help reduce body weight and waist circumference, important factors in improving metabolic conditions.
• Reduction of oxidative stress: Acts as an antioxidant, protecting against cellular damage that contributes to metabolic diseases.
• Improvement in metabolic syndrome: Helps treat conditions such as obesity, hypertension and dyslipidemia, which are often associated with fatty liver, diabetes and high cholesterol.

But not any form of Berberine will do. The most recommended is Berberine in phytosome form.Berbevis:the use of this patentallows to increase bioavailability(amount of Berberine absorbed) since “traditional” berberine has less than 5% bioavailability. That is, only 5% of what is ingested is absorbed. Thus, Berberine Berbevis is wrapped in a plant matrix called phytosome that allows for increased solubility and absorption of berberine x10 compared to traditional berberine. This not only makes it more absorbed, but also does not have the adverse effects (diarrhea and flatulence) of many other berberines.

DID YOU KNOW THAT…

It has an ancient botanical origin: Berberine has been used for more than 3,000 years in traditional Chinese and Indian medicine to treat various ailments, including infections and digestive problems.

Exercise-like effect on metabolism: Berberine has been described to activate AMPK (AMP-activated protein kinase), known as the "master switch of metabolism", a mechanism that is also activated by physical exercise.

CONTRAINDICATIONS:

• It should not be taken together with (in the same dose) metformin or gliclazide (as it may lead to excessively marked decreases in blood glucose)
• Pregnancy and breastfeeding
• Kidney transplant

You can find Berberine in our following product: