Folic acid

Folic acid is the synthetic and most stable form of vitamin B9, essential for cell development and red blood cell formation. It is found naturally in the form of folate in green leafy vegetables, legumes, citrus fruits, and nuts. Folic acid is especially important for women of childbearing age and during pregnancy, as it plays a key role in proper fetal development and in preventing birth defects.

Quick facts

  • El ácido fólico desempeña un papel clave en el desarrollo del feto y en la prevención de defectos congénitos

How does it work?

  • Cell formation and DNA: Participates in DNA synthesis and repair, promoting healthy cell division.
  • Homocysteine metabolism: Reduces levels of homocysteine, an amino acid that, in excess, is associated with increased cardiovascular risk.
  • Development of the fetal nervous system: It is essential for the closure of the neural tube in the first weeks of gestation, preventing birth defects.

Forms of folic acid

Folic acid (classic synthetic)

  • Most commonly used form in conventional fortification and supplements.
  • Economical and stable.
  • It needs conversion in the body to become its active form (5-MTHF).

Natural folate

  • Present in fresh foods (spinach, broccoli, legumes).
  • Lower stability and bioavailability.

Methylated folate (5-MTHF)

  • Active form, ready for use by the body.
  • Especially recommended for people with MTHFR gene mutations (affecting folic acid conversion).
  • Lower risk of accumulation of unmetabolized folic acid.