Folic acid is the synthetic and most stable form of vitamin B9, essential for cell development and red blood cell formation. It is naturally found in the form of folate in leafy green vegetables, legumes, citrus fruits, and nuts.
Quick facts
Folic acid plays a key role in fetal development and the prevention of birth defects
Folic acid is especially important for women of childbearing age and during pregnancy, as it plays a key role in the proper development of the fetus and in the prevention of birth defects.
How does it work?
- Cell and DNA formation: It participates in DNA synthesis and repair, promoting healthy cell division.
- Homocysteine metabolism: It reduces homocysteine levels, an amino acid that, in excess, is associated with a higher cardiovascular risk.
- Fetal nervous system development: It is essential for the closure of the neural tube in the early weeks of gestation, preventing birth defects.
Forms of folic acid
Folic acid (classic synthetic)
- The most commonly used form in fortification and conventional supplements.
- Economical and stable.
- It needs to be converted in the body to become its active form (5-MTHF).
Natural folate
- Present in fresh foods (spinach, broccoli, legumes).
- Less stable and bioavailable.
Methylated folate (5-MTHF)
- Active form, ready for use by the body.
- Especially recommended for people with MTHFR gene mutations (which affect folic acid conversion).
- Lower risk of accumulation of unmetabolized folic acid.
